I ran B5 1st Edition once or twice as a one shot but never ran a campaign. Another member of my group ran a 1st Edition campaign, one I was not involved with and discovered some serious issues with the balance in the game, in particular in the area of Telepaths.
Now I am considering a campaign in Second edition because I like the rules better. As for Influence and starship rules, I am not concerned. We have been playing sci-fi games for 15 years and hardly ever get into a need for starship rules. Influence I may use, I dunno.
My big concern is all this talk about compatibility. I know d20 pretty well, and I have been diving deep in my B5 books all night tonight. I do find occasional problems here and there, the biggest glaring problem is Telepath abilities, but other than that, I think I can handle most major converison issues on the fly.
We'll see how it turns out.
Ron