I didn't realize that there were any particular rules, is S&P#7 online? (never mind, I found the info thread. Gotta love the Edit button!)
I've always handle it by having the player run several of the PCs and I would do some of the others, mostly as backup and support, just like NPC henchmen, in a way. In the past several years, I've done a lot of this with my son, who is now older and is taking a greater interest in this. I've relied heavily on NPC reaction tables, and pregenerated reaction options at crucial times in the scenario. As I have a lot of RPG games, I've stolen reaction tables from all of them that had them. Luckily, most of them have 'im. I find it is important not to be too arbitrary, because (at least with my son), they start to question your motives! I don't think this has anything to do with playing Paranoia.
I find it hard to be a player and GM at the same time. The only game that I had been able to do this with is The Fantasy Trip. But mostly that was just the combat arena, never got much into role-playing that game.
Still, it is much more fun to play with at least 2 others. Otherwise, it's mostly character building.
That has been my experience. Gotto find that issue#7, might be helpful.