So there's two ways to go about it, I suppose.
There's same-but-different. Then there's the deep end.
For giggles, we'll go with the deep end. Prepare to dive.
"The Vorlon's plan was undone in the end by the death of one man: Jeffery Sinclair. Without him, without Babylon 4, the last Shadow War ended badly for the forces of Order. And the Shadows emerged stronger than they would have.
"The Earth-Minbari War began with a misunderstanding. In a moment of panic, the commander of an EarthForce expedition shot and crippled the Grey Sharlin, killing Dukhat. The enraged Minbari began a war of genocide, one which the Earth Alliance couldn't win. The end came after two years of battles, with the Battle of the Line, at which Earth itself was beseiged for six hours by Minbari forces. The line did not hold...
"The Minbari crushed the Earth Alliance, making sure the humans understood the depth of their mistake. The purge began with Mars, where the remnants of EarthForce made one final stand before fleeing to the Rim with as many civilian survivors as they could muster. As of 2245, there were no known human colonies left. To the few survivors of the genocide, refuge was found in the Abbai Matriarchy.
"The first waypoint on the EarthForce's exodus out to the Rim was Za'ha'dum, where the waking Shadows quietly observed the embittered humans, and saw only a tool to be used against the Vorlons. They sent the Drakh to the humans, who sympathized with them and spoke words of friendship. 'We too have suffered at the hands of the Minbari', said the Drakh, "They razed our worlds to the ground as they did yours, leaving us too a refugee people.' And so the claws of the Shadows gained a foothold in the remains of humanity. The dark and terrible fruit would ripen in mere decades..."