Funny that I saw this here. I have been toying (just toying mind..don't want to step on Intellectual property rights or anything) with the idea of doing a total conversion mod of Neverwinter Nights for Paranoia. Of course, that would be an insane amount of work, and would likely never see the light of day even without the intellectual property stuff.
Anyhow, there's an idea. I believe something like the NWN engine (aurora I believe it's called) would be an IDEAL candidate for a mod to make a PC version of Paranoia. I mean, it's got the great customizability, you can make your own scenarios, and you can have your friends hop on their computers and play it with you running it as the GM while they do so.
Like I said though, a lot of work (redoing all the models and tiles and artwork, not to mention "fixing" the combat system so it's no longer D20) and there is the problem that I bet Mongoose would not be the happiest camper in the world with something like that just floating out there.