TrippyHippy
Emperor Mongoose
Would a gritty, jungle based adventure setting work? Tarzan has a high profile, and has plenty of pulp literature, comics, movies and TV series behind it. It hasn't been in the public eye for some time, but it would be recognisable enough to get gamers attention, and RQII could be tailored for it - it'd be a bit different. But then, why not?