I agree that the character generation and basic mechanics work just fine for Star Trek, the Wild West, ancient Sumeria, or whatever. But Credits, SOC, Trade, are not well aligned for Star Trek, so it would be a different set of sourcebooks for sure.
And then there's Harry Mudd, so sometimes the post-materialist trappings of Star Trek look only surface deep - and Star Fleet is basically a government job, so economics are likely distorted from that point of view (says a guy with a government job who used to be an entrepreneur, but really wanted to be able to afford good insurance. Shoulda moved back to Norway...).