I haven't even seen Dilettante yet, but based on daydreaming and the preview, I have to say that I've seriously considered trying to do a "rich/powerful folks in trouble" sort of campaign based loosely on the style (though not the substance) of Star Wars. Planetary governors calling for help, turncoats and betrayals in the court, sending in a platoon of Imperial Marines first to coerce reluctant foes, etc.
Players would all be nobles of some sort (or possibly their most trusted Generals, etc.) who are going about the business of trying to maintain control of a border subsector. The players would probably find themselves being the PATRONS in many encounters as they hire locals and "untraceables" to do their dirty work. (For a very regular group, it might be fun to run those missions as one-off sessions using the other characters - the players would certainly be motivated to succeed!)
I would not really track things like money (except in some cases where they wind up in truly frontier areas who do not link in to the banking system, and then I'd play it more for laughs and frustration) or require the players to carefully manage their inventories (aside from their personal "signature" equipment). Naturally the players would have at least one ship in the 1000 ton range at their disposal, as well as a raft of competent but expendable NPCs and such.
Such a campaign would work well in either Imperial or Aslan space, or (better yet) on the border between the two.
It would certainly be a change from the Free Traders & Mercs style games at any rate.