I'd stick to having manouvre and warp drives seperate - as noted, it retains an interesting set of tradeoffs in design.
What would the setting be like?
Well, there are three critical effects for using the warp drive rules, all of which are broadly "good" from the perspective of the universe's inhabitents, but probably bad from the perspective of adventurers, tramp traders and pirates - i.e. the PCs.
1) Things cost less to import/export.
If you use warp drive with a decent (i.e. not Jump/1) drive, you use less fuel per jump and take less time - and have to carry less fuel. Which translates to massively lower running costs, which means that the cost of buying tech from offworld locally in the sector relative to making things locally.
WRT trade costs, let's do a quick thought experiment with a modified far trader (the Star Hunter was the first ship to come to hand) with a crew of four - pilot, astrogator, engineer, medic (astrogator and medic doing double duty as gunners where needed).
That leaves two empty staterooms (which we'll ignore or use as common rooms), and the 38 dTons of cargo (which we'll assume you manage to fill every time).
OTU/Jump Drive
Assuming negligible layover time, you can make two return trips between adjacent systems in a month. That means you've shifted 152 dTons.
In doing so you've spent Cr 45,991 on crew salaries, maintenance and life support.
You've also burned 172 dTons of fuel, which, assuming you bought it refined, costs a further Cr 86,000.
That's a net cost of Cr 131,991 to divide up across 152 dTons, or a base cost of Cr 869/dTon
YTU/Warp Drive
Assuming negligible layover time, you can make four return trips between adjacent systems in a month (only takes 3.5 days). That means you've shifted 304 dTons.
In doing so you've spent Cr 45,991 on crew salaries, maintenance and life support.
You've also burned 24 dTons of fuel, which, assuming you bought it refined, costs a further Cr 12,000.
More importantly, assuming your ship is suitably redesigned, the 40 dTons which were used to hold your jump fuel can now hold 40 dTons more cargo, which over your four return trips is another 320 dTons of cargo.
That's a net cost of Cr 57,991 to divide up across 624 dTons, or a base cost of Cr 93/dTon
To translate - in a warp drive universe interstellar commerce has one tenth the overheads, meaning (inter)globalization is far more viable. You're less likely to see a variation in TL amongst the prosperous classes on worlds in a region, because it's so easy to buy the latest off-world software/gadget/etc.
As a result, expect to see manufacturing bases concentrated on single worlds in a region - because it's more cost effective to have a single big complex cover several local systems - but equally, to have the technology available be much more standardised, because worlds which can't make high TL stuff can buy it in more easily.
2) You can govern a local area more effectively
At a 3-4 parsec wide cluster of systems level (so, less-than subsector), you can maintain much tighter local control from administrative centres. Expect a level of authority between planetary nobles and subsector dukes to represent the real day-to-day management, because you can centralise (which governments like) but a Warp-6 ship can get take a query to another system 1 parsec away, come back with a request for clarification, take additional information there again and come back with the final decision faster than a jump drive ship could get there in the first place...
3) Systems are more heavily developed
If you have a Warp-1 drive, then the system's asteroid belt, gas giants, etc are minutes away, if that. Exit a world's 100D limit and hit warp and you can be anywhere else in the system in a very small period of time. Result: if there is anything worth exploring or exploiting elsewhere in the system, someone will do it. It is far more cost-effective to maintain mining outposts on other worlds or mineral-rich asteroids because frankly you could commute to them if you really wanted to. An inhabited system will be a lot busier throughout, not just near the mainworld.