Beginning 2015, I ran a 1.5 year long Mongoose 1E campaign in the Spinward Marches, I tainted it with Vargr from Gvurrdon Sector. The two versions of the latter that I discovered, one being Mongoose, I find there is much story to be seen from the Vargr Extents. Like the Marches, Gvurrdon is the meeting point between the Imperium Humans, Client State Humans, Zhodani, Imperial Vargr (the Aekhu ethnicity), and the Extents Vargr (Gvegh and Logaksu to Trailing ethnicities).
I find that the years of 1105 through 1201 are tumultuous, frontier, and wracked with rapid changes at times that challenge the players, their characters and give plenty of ammunition to the Referee.
Were I to run another campaign of Traveller, I would choose Gvurrdon as a base and then introduce elements from the Zhodani Consulate, the Third Imperium and the myriad polities of the Vargr Extents. I would like to see a less sanitary version of the Sector be presented in more gritty light. Space can be ugly and the meeting of the various sophonts there is no less story-worthy than the Spinward Marches.