Usually it’s the seals around access points (doors), pass-thrus (for wiring, fluids, etc) and joins between panels/parts/modules that are of greatest risk. The firewall in a car has at least a half-dozen of these points, none of which are pressure-tight. Electrical connectors designed to meet IP-67 (a high standard in the automotive world for resisting moisture ingression) are only tested to 1 meter depth.
Given the variety of environments a Traveller spacecraft encounters I would expect the standards for it to be higher. But something close to IP-67 might be common for civilian in-atmosphere vehicles.