A Computer result is like jerking the wheel when someone else is driving. Try to be memorable, then try for fun, then try to reinforce paranoia.
1) R&D equipment should malfunction or be wildly dangerous on a Computer result. Using an experimental device should produce spectacular results. Paired with a few successes, the device can over-achieve its intended purpose -- a weapon will destroy the target with massive collateral damage (sometimes another clone), other devices can create environmental or other complications for the user. If a player is expecting/hoping to turn their R&D device into a bomb or relying on something spectacular happening, then it should malfunction by doing nothing.
2) Friend Computer being helpful is a go-to with normal actions. Make it funny, and maybe apply twisted logic that doesn't work. "Coretech Popup: I see you are trying to hide from your fellow Troubleshooters! I can help! Broadcast: Hey, citizens! Sneak-Y is absolutely not at this location! [The crates next to the door are now pixellated.]" "You are attempting to disarm a Mark IV Warbot. It's titanium shell is impenetrable to weapons fire. Kung-Fu module downloading...."
3) Think about what the Troubleshooter is trying to do, and have Friend Computer help in some way that makes it more tense/funny. Another standby: "Your shot at the targeting clone should hit, but deviating a millimeter will cause collateral damage to the Hot Fun pipes behind him! Collateral damage is treason!"
4) Friend Computer can cause complications by catching players doing something potentially treasonous. "I see that you are attempting to shoot an innocent citizen! Aim here! Your Treason Rating has increased!" "For sanitary reasons, please do not dispose of clone bodies inside that crate. There's an access hatch to the Food Vats just around the corner." Sometimes the Computer won't say anything, because it's IntSec who just monitored the clone and added +1 Treason Star.
5) After a while, the other players might give helpful suggestions. This is a great solution to get everyone involved, and into the mood of messing with each other.
6) I see that you are trying to create a list of helpful options! Do you want to know more? Please fill out Form CL1P-Y-WIN-D0 and we will be right back to you within 2 daycycles! Would you like to take our survey to tell us how wonderful and loyal you are to Friend Computer?